The slides used in the Tuesday and Thursday lectures will be posted here, shortly after the class.
Lecture 2, 10 January
- Introductions to pH and Buffers, and UV-visible Spectroscopy
Lecture 5, 22 January
- UV-visible Spectrophotometry: Beer's Law and Measuring Protein Concentration
Lecture 6, 24 January
- Dealing with Uncertainties and Introduction to Curve Fitting
Lecture 11, 12 February
- Emzyme Kinetics Continued
Due to a video system problem, this lecture was delivered without any slides. But, the slides that would have been used are available for download. These slides include ones that would have been used for clicker questions, but without the correct answers indicated. You are encouraged to give some thought to these questions.
Lecture 14, 21 February
- Energy Profiles for Enzymatic Reactions and Making Insulin with Trypsin
Lecture 16, 28 February
- Reversible Inhibition Mechanisms, &beta-Secretase Inhibitors and Introduction to Irreversible Inhibitors
- A short news article about current approaches to developing drugs for Alzheimer's Disease just appeared on a web site covering biotechnology. Be aware that this is not a peer-reviewed article, but rather is published by an industry newsletter that may tend towards promoting the industry. Still, it is a good follow up to today's lecture.
Lecture 18, 19 March
- Introduction to Electrophoresis and Thiol-Disulfide Chemistry
Lecture 19, 31 March
- More on Disulfides and Protein Folding: The Anfinsen Experiment