The slides used in the Tuesday and Thursday lectures will be posted here, shortly after the class.

Lecture 1, 8 January
Lecture 2, 10 January
Lecture 3, 15 January
Lecture 4, 17 January
Lecture 5, 22 January
Lecture 6, 24 January
Lecture 7, 29 January
Lecture 8, 31 January
Lecture 9, 5 February
Lecture 10, 7 February
Lecture 11, 12 February
  • Enzyme Kinetics Continued
    Due to a video system problem, this lecture was delivered without any slides. But, the slides that would have been used are available for download. These slides include ones that would have been used for clicker questions, but without the correct answers indicated. You are encouraged to give some thought to these questions.
    Download slides (pdf)
Lecture 12, 14 February

Lecture 13, 19 February
Lecture 14, 21 February
Lecture 15, 26 February
Lecture 16, 28 February
  • Reversible Inhibition Mechanisms, & beta-Secretase Inhibitors and Introduction to Irreversible Inhibitors
    Download slides (pdf)
  • A short news article about current approaches to developing drugs for Alzheimer's Disease just appeared on a web site covering biotechnology. Be aware that this is not a peer-reviewed article, but rather is published by an industry newsletter that may tend towards promoting the industry. Still, it is a good follow up to today's lecture.
Lecture 17, 5 March
Lecture 18, 19 March
Lecture 19, 31 March
Lecture 20, 26 March
Lecture 21, 28 March
Lecture 22, 2 April
Lecture 23, 4 April
Lecture 24, 9 April
  • Introduction to Chromatography and Gel Filtration
    Download slides (pdf)
  • Chromatography Handbooks Many of the chromatography media most commonly used for biochemistry were developed by Pharmacia Fine Chemicals, now a part of GE Healthcare. For many years, Pharmacia published free handbooks on the use of these materials, and updated versions are available for download. The handbooks for size exclusion (gel filtration) and ion exchange chromatography are particularly useful:
Lecture 25, 11 April
Lecture 26, 16 April
Lecture 27, 18 April